A Research Study On Stem Cell Therapy - 1511 Words

Introduction Stem cells are homogeneous cells found in the human body which have potential to change into, or differentiate into a range of specific types of cells (Stoppler, 1996). The refurbishment and protection of many adult tissues are safeguarded by stem cells (SCs) which exist in the top of the cellular sorting section of these tissues (Beck, 2013). Practical assessments, such as transplantation, in vitro clonogenic assesses (technique used to study efficacy of exact agents in terms of the proliferation and endurance of cells) and in vivo lineage tracing, have been undertaken to evaluate the repairing and differentiation capability of normal SCs (Beck, 2013). Currently, research is on-going to resolve whether stem cell therapy is†¦show more content†¦Minimal research findings and reports have been written on the role of side population (SP) cells in human nasopharyngeal carcinoma (NPC). This literature review will evaluate the 2007 research article on, â€Å"Identification of Ca ncer Stem Cell-Like Side Population Cells in Human Nasopharyngeal Carcinoma Cell Line,† by Wang, Guo, Chen, Zeng and Lu, and determine whether SP cells in human NPC are viable as an aid in efficient drugs and therapeutic strategies which target NPC Cancer stem cells (CSC) (Wang, Guo, Chen, Zeng, Lu, 2007). Review of Underpinning Science Cancer stem cells (CSCs) give rise to the movement of cancer from one section of the body to another, and are located in several tumour varieties. The unique properties of stem cells which make them different from normal cells are; their unspecialised nature, capability to give rise to specialised cell types and ability to divide and renew themselves (Bethesda, 2015). These stem cell properties can be used to classify CSCs, and therefore can enable them to treat NPC. A major result of this manipulation process is the ability the cell can have to extrude dyes such as Hoechst 33342 through the ATP binding cassette (which encloses membrane proteins that transfer an extensive array of substrates) (Dean, 2002)(Wu, C., Alman, B. A., 2008). Importantly, SP cells are a source of research as they contain these stem cell characteristics and are therefore able to exclude the Hoechst 33342 dye. This